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Palmitoyl Tetrapeptide-7

 

Chemical name (INCI):
Palmitoyl Tetrapeptide-7
Function:
SKIN CONDITIONING

This peptide was designed to reduce inflammatory processes in the skin and reduce the consequences of skin inflammation.

Palmitoyl Tetrapeptide-7 is a synthetic peptide comprised of four amino acids. As with palmitoyl hexappetide-12, palmitic acid is attached to the peptide chain as a penetration enhancer to drive the peptide through the stratum corneum.

Inflammation is normally a protective response to tissue injury or destruction and is an important part of the body’s immune response. When inflammation is experienced, the skin releases inflammatory mediators – interleukins.  Up to about age 35, when hormone levels begin to drop, the hormonal regulatory system begins to break down and significant levels of interleukins are found in the skin even when there is no inflammatory stimulus. This results in slow tissue regeneration, tissue rigidity and a loss of healing potential. All this affects the skin’s support system – collagen, elastin and other proteins – and leads to wrinkles, sagging, loss of youthful contours and uneven skin tone.

UV radiation is known to accelerate interleukin production. When the scientists exposed cells to UV radiation and then added palmitoyl tetrapeptide-7, they achieved an 86% reduction in interleukin production.

Palmitoyl tetrapeptide-7 inhibits the release of interleukins, reduces inflammation and thereby reduces the aging process in the skin and helps the skin regenerate. In vitro, Ultra Aesthetics’ scientists have shown that depending on the dose, palmitoyl tetrapeptide-7 can reduce the release of interleukins by 40%.

SCIENTIFIC ARTICLES:
http://www.green-river.eu/English/Downloads/Palmitoyl%20Oligopeptide.pdf